Publications

• Tumor necrosis factor-a-induced sickness behavior is impaired by central administration of an inhibitor of c-Jun N-terminal kinase

Psychopharmacology, 2008

 

• D-JNKI, a peptide inhibitor of c-Jun N-terminal kinase, promotes functional recovery after transient focal cerebral ischemia in rats. 
  

Neuroscience, 2008

 

• p38a suppresses normal and cancer cell proliferation by antagonizing the JNK–c-Jun pathway

Nature Genetics, 2007

 

• Intratympanic treatment of acute acoustic trauma with a cell-permeable JNK ligand: a prospective randomized phase I/II study

Informa Healthcare, 2007

 

• Inhibition of the c-Jun N-Terminal Kinase-Mediated Mitochondrial Cell Death Pathway Restores Auditory Function in Sound-Exposed Animals

Molecular Pharmacology, 2007

 

• Time-course of c-Jun N-terminal kinase activation after cerebral ischemia and effect of d-JNKI1 on c-Jun and caspase-3 activation

Neuroscience, 2007

 

• Blocking c-Jun-N-terminal kinase signaling can prevent hearing loss induced by both electrode insertion trauma and neomycin ototoxicity

Hearing Research, 2007

 

• Modulation of amyloid-b-induced and age-associated changes in rat hippocampus by eicosapentaenoic acid

Journal of Neurochemistry, 2007

 

• AM-111 Reduces Hearing Loss in a Guinea Pig Model of Acute Labyrinthitis

The Laryngoscope, 2007

 

• AM-111 protects against permanent hearing loss from impulse noise trauma.

Hearing Research, 2007

 

• A peptide inhibitor of c-Jun NH2-terminal kinase reduces myocardial ischemia reperfusion injury and infarct size in vivo

Am J Physiol Heart Circ Physiol, 2007

 

• Novel Strategy for Treatment of Viral Central Nervous System Infection by Using a Cell-Permeating Inhibitor of c-Jun N-Terminal Kinase.

Journal of virology, 2007

 

• The c-Jun N-terminal kinase JNK participates in cytokine and isolation stress-induced rat pancreatic islet apoptosis

Diabetologia, 2007

 

• Blocking c-Jun-N-terminal kinase signaling can prevent hearing loss induced by both electrode insertion trauma and neomycin ototoxicity

Hearing Research, 2006

 

• Saturated fatty acids inhibit induction of insulin gene transcription by JNK-mediated phosphorylation of insulin-receptor substrates

Natl Acad Scie USA, 2006

 

• A Peptide c-Jun N-Terminal Kinase (JNK) Inhibitor Blocks Mechanical Allodynia after Spinal Nerve Ligation: Respective Roles of JNK Activation in Primary Sensory Neurons and Spinal Astrocytes for Neuropathic Pain Development and Maintenance

The Journal of Neuroscience, 2006

 

• C-Jun N-Terminal Kinase Mediates Tumor Necrosis Factor-. Suppression of Differentiation in Myoblasts

Endocrinology, 2006

 

• The JNK Are Important for Development and Survival of Macrophages

The Journal of Immunology, 2005

 

• D-JNKI1, a Cell-Penetrating c-Jun-N-Terminal Kinase Inhibitor, Protects Against Cell Death in Severe Cerebral Ischemia

Stroke, 2004

 

• Role of tumor necrosis factor receptor-1 in the death of retinal ganglion cells following optic nerve crush injury in mice

Brain Research, 2004

 

• A Peptide Inhibitor of c-Jun N-Terminal Kinase Protects against Both Aminoglycoside and Acoustic Trauma-Induced Auditory Hair Cell Death and Hearing Loss

The Journal of Neuroscience, 2003

 

• Activation of the c-Jun N-terminal Kinase Signaling Cascade Mediates the Effect of Amyloid-. on Long Term Potentiation and Cell Death in Hippocampus

The journal of biological chemistry, 2003

 

• A peptide inhibitor of c-Jun N-terminal kinase protects against excitotoxicity cerebral ischemia.

Nature Medicine, 2003